Preliminary results on Dietary habits, lifestyle, oral health and obesity in a case control study on adenocarcinoma gastric in Sao Paulo at A.C Camargo Cancer Center (2016-2017)
Gastric cancer is the fifth commonest incident malignancy represents 6.8% of the cancers (952,000 cases/2012)and it is the third leading cause of death by cancer for both genders worldwide 8.8% (723,000 deaths), Epidemiologic studies have shown the positive impact of the Mediterranean Diet.
CagL polymorphisms of Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
Helicobacter pylori is a Gram-negative bacterium that colonizes the gastric mucosa in humans. One of the main virulence factors of H. pylori is the cag pathogenicity island.
A novel role for the urease virulence factor in the induction of HIF-1α activity in gastric cells by Helicobacter pylori
A recently published study from our lab demonstrated that H. pylori activation of the PI3K-AKT-mTOR pathway in gastric cells, increased hypoxia-induced factor (HIF)-1α expression, which accelerated the post-translational down-regulation of Cyclin D1.
Presence of prophages gene elements in Helicobacter pylori genomes
The presence of bacteriophages related with Helicobacter pylori has been documented from the first reports about findings of these bacteria and several phages have been reported in the genome of H. pylori.
Development and validation of an enzyme-linked immunosorbent assay based on whole cell antigen for the diagnosis of Helicobacter pylori infection in Brazilian children and adults
ELISA serology to detect anti-H. pylori IgG antibody is a practical and low cost test. In our country there is no available noninvasive test widely used to diagnosis H. pylori infection.
Participation of Helicobacter pylori urease in angiogenesis
Helicobacter pylori is involved in gastric diseases such as ulcers and carcinomas. Urease is an important virulence factor produced by this bacterium.