Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype
The CDH1 gene, coding for the E-cadherin protein, is linked to gastric cancer (GC) susceptibility and tumor invasion. The human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in a portion of GC.
THE SEARCH FOR PRE-MALIGNANT GASTRIC LESIONS; THE VILLARRICA HOSPITAL GASTRIC CANCER PROGRAM
Chile has one of the highest mortality rates due to gastric cancer in the western hemisphere; this as a result of the high incidence of this malignancy and the association to a late diagnosis.
Current issues and perspective on the antimicrobial resistance of Helicobacter pylori in the Dominican Republic
The susceptibility of Helicobacter pylori to antibiotics in the Dominican Republic (DR) has not been monitored. Therefore, we analyzed genome mutations of H. pylori in Dominican patients associated with drug-resistance.
Sequencing of the cag Pathogenicity Island and vacA gene by next generation sequencing directly from gastric mucosa DNA
To date, analysis of the complete cag Pathogenicity Island and vacA gene have been carried out mainly by whole genome sequencing of H.pylori strains obtained by culture.
The profile of differentially expressed piRNAs associated to the field effect theory in gastric cancer
The knowledge about carcinogenesis and the molecular events that lead to cell transformation in gastric cancer (GC) has been a challenge to the scientific community. In this way, studies involving small non-coding RNAs have been widely explored.
Frequency of Helicobacter pylori in the population of Antioquia-Colombia and characterization of virulence genes CagA and VacA
Helicobacter pylori (Hp) is the main bacterial agent in gastroduodenal diseases.