This e-book covers Helicobacter pylori research as it looks in 2014. The discovery of the bacterium in 1982 by B.J. Marshall and R. I. Warren had a tremendous impact on basic research and clinical medicine, resulting, in the past 3 decades, in more than 34,000 published articles. The editor of this volume and the contributing authors have compiled a unique collection of chapters dealing the with the microbiology, epidemiology, clinical diagnosis and treatment of H. pylori infections in a country-specific manner, with contributors having the opportunity to present the peculiarities and specifics of Helicobacter research in their area or country without overlapping any other previously published e-book. This e-book is a useful reference for gastrointestinal physicians and medical researchers seeking the latest information related to H. pylori.
CONTENTS
CHAPTERS
1. Main Bacteriological Features of Helicobacter pylori 3
Amin Talebi Bezmin Abadi and Johannes G. Kusters
2. Virulence Factors of Helicobacter pylori 11
Yoshio Yamaoka and David Y. Graham
3. Epidemiology, Transmission and Public Health Implications of Helicobacter pylori Infection in Western Countries 25
Mónica S. Sierra, Emily V. Hastings, Katherine Fagan-Garcia, Amy
Colquhoun and Karen J. Goodman
4. Helicobacter pylori in Japan: Epidemiology, Diagnosis and Treatment 80
Hidekazu Suzuki, Toshihiro Nishizawa and Toshifumi Hibi
5. Helicobacter pylori in South-Eastern Asia 92
Sun-Young Lee
6. Helicobacter pylori in South America: Epidemiology, Diagnosis and Treatment 130
Luiz Gonzaga Coelho
7. Helicobacter pylori in Israel: Epidemiology, Pathophysiology, Diagnosis, Management and Resistance to Therapy 169
Haim Shmuely and Yaron Niv 8. Helicobacter pylori in Romania: Epidemiology, Diagnosis and
8. Treatment 183
Lidia Ciobanu, Marian Taulescu and Dan Lucian Dumitraşcu
9. Helicobacter pylori in Greece: Epidemiology, Diagnosis, and Treatment 202
Theodore Rokkas
10. Helicobacter pylori Infection in Iran: Epidemiology, Treatment and Diagnosis 216
Amin Talebi Bezmin Abadi and Johannes G. Kusters
11. Current Methods Used for the Diagnosis of Helicobacter pylori Infection 234
Francis Mégraud, Emilie Bessède and Philippe Lehours
12. Towards an Individualised Treatment of Helicobacter pylori Infection 259
Akiro Shiotani and David Y. Graham
13. Helicobacter pylori Infection and Functional Dyspepsia: Epidemiology, Diagnosis and Current Treatment 276
Marko Duvnjak, Ivan Lerotić, Neven Baršić and Vedran Tomašić
14. The Contribution of Meta-Analyses to the Treatment of Helicobacter pylori 280
Javier P.Gisbert
15. From Chronic Gastritis to Gastric Cancer: The Role of Helicobacter pylori 316
Krisztina Hagymási, László Herszényi and Zsolt Tulassay
16. Extradigestive Manifestations of Helicobacter pylori Infection: What is Proven and Unproven in 2014? 336
Natale Figura, Giulia Fiorilli, Francesco Langone, Leonardo Vaglio,
Elena Moretti 17. Helicobacter pylori Infection Up-date in Pediatric Population 396
Áron Cseh, Hedvig Bodánszky and Gábor Veress
18. Antibiotic Resistance of Helicobacter pylori: Worldwide Prevalence, Mechanisms and Impact on Therapy 411
Vincenzo de Francesco
19. Vulnerable Points of the Helicobacter pylori Story- Based on Animal and Human Observations (1975-2012) 429
Gyula Mózsik, Imre L.Szabó and József Czimmer
20. Development and Current State of Helicobacter pylori Research in Hungary 481
György Miklós Buzás
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